Selective Synthesis of Tetrasubstituted 4-(Tetrazol-5-yl)-1H-imidazoles from 2-(Tetrazol-5-yl)-2H-azirines (Eur. J. Org. Chem. 24/2014)
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چکیده
منابع مشابه
5-{40-[(5-Benzyl-2H-tetrazol-2-yl)- methyl]biphenyl-2-yl}-1H-tetrazole monohydrate
In the title compound, C22H18N8 H2O, the dihedral angle between the tetrazole rings is 69.58 (1) while the terminal phenyl ring makes dihedral angles of 26.98 (8) and 39.75 (8) with the other benzene rings. The rings of the biphenyl unit subtend a dihedral angle of 55.23 (8) . In the crystal, the solvent water molecule is linked to the main molecule via an N—H O hydrogen bond. In addition, C—H ...
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The synthesis and reactivity of tetrazol-5-yl-phosphorus ylides towards N-halosuccinimide/TMSN₃ reagent systems was explored, opening the way to new haloazidoalkenes bearing a tetrazol-5-yl substituent. These compounds were obtained as single isomers, except in one case. X-ray crystal structures were determined for three derivatives, establishing that the non-classical Wittig reaction leads to ...
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The title compound, [Mn(C(4)H(3)N(8))(2)(H(2)O)(4)]·2H(2)O, represents the first structurally characterized transition metal complex of the 1,2-bis-(tetra-zol-5-yl)ethene ligand. The complex mol-ecule occupies a special position on an inversion centre and the Mn atom has a tetra-gonally distorted octa-hedral coordination. The bis-(tetra-zolyl)ethene ligand is planar within 0.0366 (7) Å. All 'ac...
متن کاملSynthesis and pharmacological activity of 2-(2-substituted-phenyl)-3-(4-{1-[2- (1H-tetrazol-5-yl)-biphenyl-4-ylmethyl])-1H-benzoimidazol-2-yl}-phenyl)- thiazolidin-4-ones
An easy and efficient method to obtain Schiff bases of [2-(2-substituted-phenyl)-3-(4-{1-[2-(1Htetrazol-5-yl)-biphenyl-4-ylmethyl])-1H benzoimidazol-2-yl}-phenyl)thiazolidin-4-one] using different aromatic aldehydes. Reaction mixture of Schiff base (0.01 mol) and mercaptoacetic acid (0.05 mol) dissolved in dioxane (50 ml), anhydrous zinc chloride (0.008 mol) was added and refluxed for 12 hrs. T...
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2014
ISSN: 1434-193X
DOI: 10.1002/ejoc.201490066